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Invitrogen
STS1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96591
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human UBASH3B (NP_1162622)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MAQYGHPSPL GMAAREELYS KVTPRRNRQQ RPGTIKHGSA LDVLLSMGFP RARAQKALAS TGGRSVQAAC DWLFSHVGDP FLDDPLPREY VLYLRPTGPL AQKLSDFWQQ SKQICGKNKA HNIFPHITLC QFFMCEDSKV DALGEALQTT VSRWKCKFSA PLPLELYTSS NFIGLFVKED SAEVLKKFAA DFAAEAASKT EVHVEPHKKQ LHVTLAYHFQ ASHLPTLEKL AQNIDVKLGC DWVATIFSRD IRFANHETLQ VIYPYTPQND DELELVPGDF IFMSPMEQTS TSEGWIYGTS; Positive Samples: SW620, SKOV3, Mouse brain, Mouse spleen, Mouse lung, Rat brain; Cellular Location: Cytoplasm, Nucleus
靶标信息
Sts1 encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cbl-interacting protein p70; Cbl-interacting protein Sts-1; MGC15437; nm23-phosphorylated unknown substrate; SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate; suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; tyrosine-protein phosphatase STS1/TULA2; unnamed protein product
基因别名: 2810457I06Rik; p70; RGD1310357; STS-1; STS1; TULA-2; TULA2
UniProt ID: (Human) Q8TF42, (Mouse) Q8BGG7
Entrez Gene ID: (Human) 84959, (Rat) 315579, (Mouse) 72828
negative regulation of immune system process
negative regulation of protein kinase activity
negative regulation of signal transduction
platelet activation
peptidyl-tyrosine dephosphorylation
collagen-activated tyrosine kinase receptor signaling pathway
collagen-activated signaling pathway
regulation of osteoclast differentiation
negative regulation of osteoclast differentiation
negative regulation of bone resorption
regulation of release of sequestered calcium ion into cytosol
platelet aggregation
negative regulation of platelet aggregation
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