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Proteintech
STXBP1 Monoclonal Antibody (1B5B3), Biotin
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产品信息
BIOTIN-67137
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1B5B3
抗原
STXBP1 fusion protein Ag28605
偶联物
形式
Liquid
浓度
1000 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: HELTFQAMSY DLLPIENDVY KYETSGIGEA RVKEVLLDED DDLWIALRHK HIAEVSQEVT RSLKDFSSSK RMNTGEKTTM RDLSQMLKKM PQYQKELSKY STHLHLAEDC MKHYQGTVDK LCRVEQDLAM GTDAEGEKIK DPMRAIVPIL LDANVSTYDK IRIILLYIFL KNGITEENLN KLIQHAQIPP EDSEIITNMA HLGVPIVTDS TLRRRSKPER KERISEQTYQ LSRWTPIIKD IMEDTIEDKL DTKHYPYIST RSSASFSTTA VSARYGHWHK NKAPGEYRSG PRLIIFILGG VSLNEMRCAY EVTQANGKWE VLIGSTHILT PQKLLDTLKK LNKTDEEISS
靶标信息
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rbSec1; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1
基因别名: AI317162; AI326233; ANC18HA; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-sec1; NSEC1; NSEC1A; P67; Rb-sec1; RBSEC1; rbSec1A; rbSec1B; Sec1; STXBP1; Sxtbp1; UNC18; Unc18-1; UNC18A; Unc18h
UniProt ID: (Human) P61764, (Mouse) O08599, (Rat) P61765
Entrez Gene ID: (Pig) 100517927, (Human) 6812, (Mouse) 20910, (Rat) 25558
platelet degranulation
vesicle docking involved in exocytosis
neurotransmitter secretion
neuromuscular synaptic transmission
axon target recognition
regulation of synaptic vesicle priming
glutamate secretion
protein transport
synaptic vesicle maturation
regulation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic transmission, GABAergic
regulation of SNARE complex assembly
negative regulation of neuron apoptotic process
positive regulation of calcium ion-dependent exocytosis
protein stabilization
long term synaptic depression
platelet aggregation
protein localization to plasma membrane
transport
exocytosis
vesicle-mediated transport
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of exocytosis
