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Invitrogen
SULT1A1 Polyclonal Antibody
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SULT1A1 Antibody (PA5-12247) in WB
Western blot analysis of SULT1A1 in 293 cell lysates. Samples were incubated with SULT1A1 polyclonal antibody (Product # PA5-12247). Lysates: 2 µg/lane. 293 cell lysates either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SULT1A1 gene.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-12247
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 128-160 amino acids from the central region of human SULT1A1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with non-human primate based on sequence homology.
靶标信息
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aryl sulfotransferase; Aryl sulfotransferase 1; arylsulfotransferase ST1A4; CSPS; HAST1/HAST2; MGC131921; MGC5163; mSTp1; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; phenol sulfotransferase; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; phenol/aryl sulfotransferase; ST1A1; ST1A3; ST1A4; sulfokinase; Sulfotransferase 1A1; sulfotransferase, phenol preferring 1; Thermostable phenol sulfotransferase; Ts-PST
基因别名: AI266890; OK/SW-cl.88; PST; ST1A1; STP; STP1; SULT1A1
Entrez Gene ID: (Mouse) 20887
nucleotide binding
N-acetylglucosamine 6-O-sulfotransferase activity
N-acetylgalactosamine 4-O-sulfotransferase activity
aryl sulfotransferase activity
heparan sulfate 2-O-sulfotransferase activity
sulfotransferase activity
HNK-1 sulfotransferase activity
transferase activity
tyrosine-ester sulfotransferase activity
heparan sulfate 6-O-sulfotransferase activity
trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
1-phenanthrol sulfotransferase activity
3-phenanthrol sulfotransferase activity
4-phenanthrol sulfotransferase activity
trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
9-phenanthrol sulfotransferase activity
2-phenanthrol sulfotransferase activity
phenanthrol sulfotransferase activity
1-hydroxypyrene sulfotransferase activity
protein homodimerization activity
3'-phosphoadenosine 5'-phosphosulfate binding
galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
cholesterol sulfotransferase activity
hydroxyjasmonate sulfotransferase activity
transferase
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