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Invitrogen
SUPT16H Polyclonal Antibody
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产品信息
PA5-116891
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 520-695 of human SUPT16H (SPT16) (NP_0091231)
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HeLa, HCT116, Jurkat, C6, Mouse brain
Immunogen sequence: KEPHIREMKI YIDKKYETVI MPVFGIATPF HIATIKNISM SVEGDYTYLR INFYCPGSAL GRNEGNIFPN PEATFVKEIT YRASNIKAPG EQTVPALNLQ NAFRIIKEVQ KRYKTREAEE KEKEGIVKQD SLVINLNRSN PKLKDLYIRP NIAQKRMQGS LEAHVNGFRF TSVRGD
靶标信息
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT, interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chromatin-specific transcription elongation factor 140 kDa subunit; facilitates chromatin remodeling 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT; FACT 140 kDa subunit; FACT complex subunit SPT16; FACTp140; FLJ10857; FLJ14010; FLJ34357; HGNC:11465; hSPT16; suppressor of Ty 16 homolog
基因别名: CDC68; FACT140; FACTP140; SPT16; SPT16/CDC68; Supt16; SUPT16H
UniProt ID: (Human) Q9Y5B9, (Mouse) Q920B9
Entrez Gene ID: (Human) 11198, (Mouse) 114741, (Rat) 305851
DNA replication
DNA repair
nucleosome disassembly
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
positive regulation of DNA-templated transcription, elongation
regulation of signal transduction by p53 class mediator
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
biological_process
