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Invitrogen
SYNGR1 Polyclonal Antibody
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产品信息
PA1-1044
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues D(187) P S Q D S S M P Y A P Y V E P(202) of rat Synaptogyrin 1.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-1044 detects Synaptogyrin 1 in rat and mouse samples.
PA1-1044 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~25.5 kDa protein representing Synaptogyrin 1 in rat and mouse brain tissue samples.
The PA1-1044 immunogen is a synthetic peptide corresponding to residues D(187) P S Q D S S M P Y A P Y V E P(202) of rat Synaptogyrin 1. This sequence is conserved in mouse and human. The PA1-1044 immunizing peptide (Cat. # PEP-280) is available for use in neutralization and control experiments.
靶标信息
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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