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A suggested positive control is human lung tissue lysate.
PA5-20877 can be used with blocking peptide PEP-0991.
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. The exact function of SYNGR2 is unknown, but studies suggest that it may play a role in regulating membrane traffic in non-neuronal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cellugyrin; MGC102914; Synaptogyrin-2
基因别名: SYNGR2; UNQ352/PRO615
UniProt ID: (Human) O43760, (Rat) O54980
Entrez Gene ID: (Human) 9144, (Rat) 89815