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Invitrogen
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Immunogen sequence: GKVGDYFATEE SVGTQTSVRQ LQLGPKEGFS GQIQFTAPLS DKVELGVIGD SVHMEGLPGS STSIRHISIG PQRHQTTQQ
Highest antigen sequence identity to the following orthologs - mouse 55%, rat 54%.
Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。