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Proteintech
SYTL5 Polyclonal Antibody
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产品信息
24528-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SYTL5 fusion protein Ag21698
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: TQQEASRVCV HCHRNLGLIF DRGDPCQACS LRVCRECRVA GPNGSWKCTV CDKIAQLRII TGEWFFEEKA KRFKQVNVLG TDVVRQSILR RSPGAEEVQS QEQTRQDAEK SDTSPVAGKK ASHDGPKRKG FLLSKFRSAT RGEIITPKTD TGRSYSLDLD GQHFRSLKSP PGSDRGSTGS SDLNDQEPGP RTPKSSRSNG VTPGTQSSPA PSTRTVTSVI SREYGFENSM DLAAIEGTSQ ELTKSHRRNT SGTPSIAVSG TSLSSDQSRS ELDLSESFTE DSEDTVSI
靶标信息
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: exophilin 9; synaptotagmin 15; synaptotagmin-like 5; Synaptotagmin-like protein 5
基因别名: ENSMUSG00000054453; SLP5; SYTL5
UniProt ID: (Human) Q8TDW5, (Mouse) Q80T23, (Rat) Q812E4
Entrez Gene ID: (Human) 94122, (Mouse) 236643, (Rat) 302538
