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Nordic
Saccharomyces 6-Phosphogluconic dehydrogenase Polyclonal Antibody
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产品信息
NE128-PAB
产品规格
种属反应
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Saccharomyces 6-Phosphogluconic dehydrogenase
偶联物
形式
Lyophilized
浓度
2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 0.5% dextran
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstituted by adding 0.5 mL sterile distilled water, spun down to remove insoluble particles, divided into small aliquots, frozen and stored at or below -20°C.
Cross-reactivities against enzymes of other sources may occur but have not been determined.
Prior to use, an aliquot is thawed slowly at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used t he same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the product.
靶标信息
6-Phosphogluconic acid, also known as 6-phospho-D-gluconate or gluconate 6-phosphate, belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. 6-Phosphogluconic acid is soluble (in water) and a moderately acidic compound (based on its pKa). 6-Phosphogluconic acid has been found in human adipose tissue, epidermis and prostate tissues, and has also been detected in multiple biofluids, such as saliva and blood. Within the cell, 6-phosphogluconic acid is primarily located in the endoplasmic reticulum. 6-Phosphogluconic acid exists in all eukaryotes, ranging from yeast to humans. 6-Phosphogluconic acid participates in a number of enzymatic reactions. In particular, 6-Phosphogluconic acid can be biosynthesized from gluconolactone and water through the action of the enzyme 6-phosphogluconolactonase. In addition, 6-Phosphogluconic acid can be converted into D-ribulose 5-phosphate; which is catalyzed by the enzyme putative uncharacterized protein PGD. In humans, 6-phosphogluconic acid is involved in the pentose phosphate pathway. 6-Phosphogluconic acid is also involved in several metabolic disorders, some of which include glucose-6-phosphate dehydrogenase deficiency, ribose-5-phosphate isomerase deficiency, transaldolase deficiency, and cancer (via the Warburg effect). Outside of the human body, 6-phosphogluconic acid can be found in a number of food items such as white lupine, american pokeweed, peach, and star anise. This makes 6-phosphogluconic acid a potential biomarker for the consumption of these food products.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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