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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
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Immunogen sequence: MAYFDPDFYA SAPGHKHVPD WV
Highest antigen sequence indentity to the following orthologs: Rat - 91%, Mouse - 91%.
The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. A pseudogene of this locus has been identified on chromosome 7.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ethanolaminephosphotransferase 1; hEPT1; Selenoprotein I; SelI
基因别名: EPT1; KIAA1724; SELENOI; SELI
Entrez Gene ID: (Human) 85465