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Alomone Labs, LTD
Semaphorin 6A (extracellular) Polyclonal Antibody
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图: 1 / 4
Semaphorin 6A (extracellular) Antibody (ASR-071-200UL) in IHC (F)
Expression of Semaphorin 6A in rat cerebellum. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-Semaphorin 6A (extracellular) Antibody (#ASR-071), (1:400), followed by donkey Anti-rabbit-biotin and Streptavidin-Cy3. A. Semaphorin 6A immunoreactivity (red) appears in the molecular layer (MOL) and in the Purkinje cell layer (P) (arrows). B. Pre-incubation of the Antibody wit... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ASR-071-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)NHQDKKGVIRESYLK, corresponding to amino acid residues 626-640 of mouse Semaphorin 6A, Extracellular, N-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Mutant line 997; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; sema Q; sema VIA; SEMA6A-1; semaphorin 6A-1; semaphorin Q; semaphorin VIA; semaphorin-6A-1; unnamed protein product
基因别名: A730020P05Rik; HT018; SEMA; Sema6A-1; SEMA6A1; SEMAQ; VIA
UniProt ID: (Human) Q9H2E6, (Mouse) O35464
Entrez Gene ID: (Human) 57556, (Rat) 361324, (Mouse) 20358
neural crest cell migration
neuron migration
cell surface receptor signaling pathway
axon guidance
negative regulation of angiogenesis
cellular response to vascular endothelial growth factor stimulus
centrosome localization
negative regulation of ERK1 and ERK2 cascade
semaphorin-plexin signaling pathway
negative regulation of cell adhesion involved in sprouting angiogenesis
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of sprouting angiogenesis
positive regulation of neuron migration
apoptotic process
negative chemotaxis
cytoskeleton organization
nervous system development
organ morphogenesis
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