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Immunogen sequence: NKVKETELEL KEKERELHEK FEHLKRVHQE EKRKVEEKRR ELEEETNAFN RRKAAVEALQ SQALHATSQQ PLRKDKDKKN; Positive Samples: U-251MG, HeLa, LO2, Mouse heart, Mouse kidney, Rat brain; Cellular Location: Cytoplasm, cytoskeleton
SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking (Blaser et al., 2003 [PubMed 12909369]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2-Sep; sept8 {ECO:0000312|EMBL:AAI58797.1, ECO:0000312|RGD:1308449}; Septin-8; septin-8 {ECO:0000250|UniProtKB:Q8CHH9}
基因别名: AW046166; KIAA0202; mKIAA0202; SEP2; Sepl; SEPT8; SEPTIN8
UniProt ID: (Human) Q92599, (Mouse) Q8CHH9
Entrez Gene ID: (Human) 23176, (Rat) 303135, (Mouse) 20362