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Sphingosine 1 Phosphate Receptor 5 CT (EDG-8) Polyclonal Antibody
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产品信息
X1094P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Unique synthetic peptide derived from the C-terminus of the human EDG-8 protein
偶联物
形式
Liquid
浓度
0.5-2 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
0.08% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: RH7777 cells transfected with full length EDG8 protein.
Detects recombinant EDG8 receptors by Western blot at 42 kDa. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development.
靶标信息
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; S1P receptor 5; S1P receptor Edg-8; S1P(5) receptor; Sphingosine 1-phosphate receptor 5; Sphingosine 1-phosphate receptor Edg-8; sphingosine 1-phosphate receptor EDG8
基因别名: Edg-8; EDG8; S1P5; S1PR5; SPPR-1; SPPR-2
UniProt ID: (Human) Q9H228
Entrez Gene ID: (Human) 53637
