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Invitrogen
Spinesin Polyclonal Antibody
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产品信息
PA5-31485
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human Spinesin. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: MCF-7, mouse brain.
Predicted reactivity: Human (99%), Mouse (87%), Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC141886; MGC148044; Spinesin; Transmembrane protease serine 5
基因别名: SPINESIN; TMPRSS5
UniProt ID: (Human) Q9H3S3, (Mouse) Q9ER04
Entrez Gene ID: (Human) 80975, (Mouse) 80893
