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Invitrogen
Sulfa synergist agent Recombinant Mouse Monoclonal Antibody (4B3)
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Sulfa synergist agent Antibody (MA566303) in SDS-PAGE
SDS-PAGE characterization of Sulfa synergist agent under reducing conditions. Lane M: Protein marker (kDa); Lane SSA: Purified Sulfa synergist agent Recombinant Monoclonal (Product # MA566303). Sulfa synergist agent showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-394.
产品信息
MA566303
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4B3
抗原
Conjugate of SSA hapten and KLH.
偶联物
形式
Liquid
浓度
4.3 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Sulfa synergist agents, such as sulfamethoxazole, are known for their ability to enhance the antibacterial effects of other drugs, particularly trimethoprim. This synergistic effect is achieved through the simultaneous binding of both drugs to the bacterial enzyme dihydrofolate reductase, leading to a more potent inhibition of bacterial growth. Sulfa drugs are synthetic bacteriostatic antimicrobials that were widely used before the advent of penicillin. They function by interfering with the synthesis of folate within bacterial cells, a crucial component for bacterial DNA replication and cell division. The combination of sulfa drugs with trimethoprim is particularly effective against Escherichia coli and other bacterial infections, providing a chemotherapeutic potentiation that enhances the overall efficacy of treatment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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