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Invitrogen
Synaptojanin 2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-56784
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.7 mg/mL
规格
70 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HGQYSILQTA RLLPGAPQQP PKARTGISKP YNVKQIKTTN AQEAEAAIRC LLEARGGASE EALSAVAPRD LEASSEP
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.
靶标信息
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: inositol phosphate 5'-phosphatase 2; inositol polyphosphate 5'-phosphatase; inositol polyphosphate-5-phosphatase H; phosphatidyl inositol phosphatase; phosphoinositide 5-phosphatase; phosphoinositide phosphatase; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2; synaptojanin-2; unnamed protein product
基因别名: INPP5H; mKIAA0348; SJ2
UniProt ID: (Human) O15056, (Mouse) Q9D2G5, (Rat) O55207
Entrez Gene ID: (Human) 8871, (Mouse) 20975, (Rat) 84018
nucleic acid binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
protein binding
phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
phosphatidylinositol phosphate phosphatase activity
SH3 domain binding
PDZ domain binding
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol monophosphate phosphatase activity
inositol phosphate phosphatase activity
receptor-mediated endocytosis
phosphatidylinositol metabolic process
phosphatidylinositol dephosphorylation
clathrin coat assembly
synaptic vesicle endocytosis
inositol phosphate catabolic process
phosphatidylinositol biosynthetic process
phosphatidylinositol-3-phosphate biosynthetic process
membrane organization
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