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Invitrogen
Syntaxin 1 Monoclonal Antibody (SP6), Biotin
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产品信息
MA5-17613
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
SP6
抗原
Human Syntaxin
偶联物
Biotin
Biotin
Biotin
形式
Liquid
浓度
0.1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS with 4-5mg/mL BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-17613 targets Syntaxin-1 in ELISA, FACS, and WB applications and shows reactivity with Human, Mouse, and Rat samples.
The MA5-17613 immunogen is human Syntaxin.
靶标信息
Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: neuron-specific antigen HPC-1; P35A; SNARE protein; STX1A; STX1B; STX1B1; STX1B2; STXA1; synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; Syntaxin-1B1; Syntaxin-1B2; unnamed protein product
基因别名: HPC-1; P35-1; STX1; SYN1A
UniProt ID: (Human) Q16623, (Rat) P32851, (Mouse) O35526
Entrez Gene ID: (Human) 6804, (Rat) 116470, (Mouse) 20907
SNARE binding
SNAP receptor activity
protein binding
myosin binding
calcium channel inhibitor activity
chloride channel inhibitor activity
kinase binding
protein binding, bridging
myosin head/neck binding
identical protein binding
ATP-dependent protein binding
ion channel binding
macromolecular complex binding
calcium-dependent protein binding
protein carrier chaperone
positive regulation of neurotransmitter secretion
intracellular protein transport
exocytosis
vesicle fusion
neurotransmitter secretion
response to gravity
positive regulation of norepinephrine secretion
regulation of synaptic vesicle priming
synaptic vesicle exocytosis
vesicle-mediated transport
protein sumoylation
regulation of exocytosis
insulin secretion
secretion by cell
positive regulation of catecholamine secretion
SNARE complex assembly
SNARE complex disassembly
regulated exocytosis
positive regulation of exocytosis
positive regulation of calcium ion-dependent exocytosis
hormone secretion
synaptic vesicle endocytosis
regulation of insulin secretion
protein localization to membrane
modulation of excitatory postsynaptic potential
positive regulation of excitatory postsynaptic potential
neurotransmitter transport
regulation of dopamine secretion
calcium ion regulated exocytosis
regulation of secretion by cell
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