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Invitrogen
TACR2 Polyclonal Antibody
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TACR2 Antibody (PA5-91934) in WB
Western blot analysis of TACR2 in extracts of various cell lines. Samples were incubated with TACR2 Polyclonal antibody (Product # PA5-91934) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-91934
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 319-398 of human TACR2 (NP_0010482)
偶联物
形式
Liquid
浓度
2.78 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RLAFRCCPWV TPTKEDKLEL TPTTSLSTRV NRCHTKETLF MAGDTAPSEA TSGEAGRPQD GSGLWFGYGL LAPTKTHVEI; Positive Samples: SGC-7901, A-549; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neurokinin 2 receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; seven transmembrane helix receptor; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin receptor 2
基因别名: NK2R; NKNAR; SKR; TAC2R; TACR2
UniProt ID: (Human) P21452
Entrez Gene ID: (Human) 6865
muscle contraction
cell surface receptor signaling pathway
tachykinin receptor signaling pathway
chemical synaptic transmission
excretion
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of smooth muscle contraction
response to electrical stimulus
prolactin secretion
positive regulation of uterine smooth muscle contraction
