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Proteintech
TAF1C Polyclonal Antibody
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产品信息
13341-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TAF1C Fusion Protein Ag4164 (565-869 aa encoded by BC028131)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IGLAAVVPP MPSAPTPGLV LFQLSAAGDV FYQQLRPQVD SSLRRDAGPP GDTQPDCHAP TASWTSQDTA GCSQWLKALL KVPLAPPVWT APTFTHRQML GSTELRREEE EGQRLGVLRK AMARGQLLLQ RDLGSLPAAE PPPAPESGLE DKLSERLGEA WAGRGAAWWE RQQGRTSEPG RQTRRPKRRT QLSSSFSLSG HVDPSEDTSS PHSPEWPPAD ALPLPPTTPP SQELTPDACA QGVPSEQRQM LRDYMAKLPP QRDTPGCATT PPHSQASSVR ATRSQQHTPV LSSSQPLRKK PRMGF (565-869 aa encoded by BC028131)
靶标信息
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RNA polymerase I-specific TBP-associated factor 110 kDa; SL1, 110kD subunit; TAFI110; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit C
基因别名: MGC:39976; SL1; TAF1C; TAFI110; TAFI95
UniProt ID: (Human) Q15572
Entrez Gene ID: (Human) 9013
regulation of transcription, DNA-templated
transcription from RNA polymerase I promoter
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
