Invitrogen

TALPID3 Polyclonal Antibody

Name: TALPID3 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-100345
Availability: InStock

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (2)

图: 1 / 2

TALPID3 Antibody (PA5-100345) in WB

Western blot analysis of TALPID3 in various samples (Lane 1: HeLa, treated with blocking peptide, Lane 2: HeLa, Lane 3: COS-7). Samples were incubated with TALPID3 polyclonal antibody (Product # PA5-100345).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image TALPID3 Polyclonal Antibody

产品信息

PA5-100345

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse, Non-human primate

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human KIAA0586(Accession Q9BVV6), corresponding to amino acid residues D375-H425.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2815812

产品详细信息

Antibody detects endogenous levels of total TALPID3.

靶标信息

KIAA0586 also named as Talpid3 is a 1472 amino-acid protein, which belongs to Talpid3 family. Talpid3 is a gene essential for vertebrate development. Studies in chicken, mouse, zebrafish and human have shown that TALPID3 is a centrosomal protein, mutants null for TALPID3 fail to produce cilia, resulting in far reaching signaling defects such as polydactyly, dorsalised neural tube, craniofacial and vascular defects often due to abnormalities in Hedgehog signal transduction. Talpid3 is absolutely required for the function of both Gli repressor and activator in the intracellular Hedgehog pathway and ciliogenesis. TALPID3 may be identified as a subcellular maker of centrosome and needed to further studied.

仅用于科研。不用于诊断过程。未经明确授权不得转售。