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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
In Western blot applications, this antibody detects a band at ~70kDa. A suggested positive control is human spleen tissue lysate.
PA5-19985 can be used with blocking peptide PEP-0109.
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CRL1IL-27R; il-27 receptor