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Invitrogen
TCF3/TCF4 Monoclonal Antibody (6F12-3)
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产品信息
MA1-25418
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
6F12-3
抗原
His-tagged fusion protein corresponding to amino acids 31-331 of human TCF.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.53 mg/mL
规格
25 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with b catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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