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Invitrogen
TDH Polyclonal Antibody
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TDH Antibody (PA5-119260) in IHC (P)
Immunohistochemistry analysis of L-Threonine Dehydrogenase in paraffin-embedded Human Cerebrum tissue. Samples were incubated with polyclonal antibody (Product # PA5-119260) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-119260
产品规格
种属反应
Human,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein L-Threonine Dehydrogenase. The antigen corresponds to amino acid range 1-229 of the target protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene appears to be an evolving pseudogene of L-threonine 3-dehydrogenase (TDH). In both prokaryotes and eukaryotes, TDH catalyzes the first of two steps in one of two L-threonine degradation pathways. However, in human, the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins. This suggests that the human gene is therefore a pseudogene. Transcripts of this gene are found in all tissues and alternatively spliced transcripts have been described. It is not known if these transcripts are translated, or if the possible protein product provides any functional role.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: L-threonine 3-dehydrogenase; L-threonine 3-dehydrogenase, mitochondrial; L-Threonine Dehydrogenase; TDH
基因别名: SDR14E1P; TDH
UniProt ID: (Pig) Q8MIR0
Entrez Gene ID: (Pig) 397065, (Human) 157739
