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Invitrogen
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Immunogen sequence: HLLKHCFGRRS ATVIDHLRSL TPLDARDILM QIGKQEDEKV VNMHPQDFKT LFETIERSKD CAYKWLYDET LED
Highest antigen sequence identity to the following orthologs - mouse 54%, rat 54%.
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。