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Proteintech
TFDP1 Polyclonal Antibody
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产品信息
11043-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TFDP1 Fusion Protein Ag1511 (1-410 aa encoded by BC011685)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAKDAGLIE ANGELKVFID QNLSPGKGVV SLVAVHPSTV NPLGKQLLPK TFGQSNVNIA QQVVIGTPQR PAASNTLVVG SPHTPSTHFA SQNQPSDSSP WSAGKRNRKG EKNGKGLRHF SMKVCEKVQR KGTTSYNEVA DELVAEFSAA DNHILPNESA YDQKNIRRRV YDALNVLMAM NIISKEKKEI KWIGLPTNSA QECQNLEVER QRRLERIKQK QSQLQELILQ QIAFKNLVQR NRHAEQQASR PPPPNSVIHL PFIIVNTSKK TVIDCSISND KFEYLFNFDN TFEIHDDIEV LKRMGMACGL ESGSCSAEDL KMARSLVPKA LEPYVTEMAQ GTVGGVFITT AGSTSNGTRF SASDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE DDDFNENDED D (1-410 aa encoded by BC011685)
靶标信息
DP family contains at least two members, DP1 and 2. Structurally, DP1 and 2 are relatively conserved, yet their expression appears to be tissue specific. E2F 1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AS1; ASRT1; cell cycle regulatory transcription factor DP1; down-regulated in liver cancer stem cells; DP; DRTF1; DRTF1-polypeptide 1; E2F dimerization partner 1; E2F-related transcription factor; MGC49004; OTTHUMP00000018767; Transcription factor Dp-1
基因别名: DILC; Dp-1; DP1; DRTF1; TFDP1
UniProt ID: (Human) Q14186, (Mouse) Q08639
Entrez Gene ID: (Human) 7027, (Rat) 361178, (Mouse) 21781
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell proliferation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of fat cell proliferation
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
mitotic cell cycle
regulation of transcription, DNA-templated
epidermis development
anoikis
positive regulation of transcription, DNA-templated
regulation of DNA biosynthetic process
transcription from RNA polymerase II promoter
cell cycle
