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Invitrogen
TFPI Polyclonal Antibody
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TFPI Antibody (PA5-47428) in WB
Western blot analysis of TFPI in 0.2 mg/mL lysates of mouse placenta tissue. Samples were incubated in TFPI polyclonal antibody (Product # PA5-47428) using a dilution of 100 µg/mL followed by HRP-conjugated Anti-Goat IgG at a dilution of 0.0763888888888889. A specific band was detected for TFPI at approximately 50-60 kDa (as indicated). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system..
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-47428
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse TFPI Leu29-Lys289
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human TFPI and less than 5% cross-reactivity with recombinant mouse TFPI-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: extrinsic pathway inhibitor; Kunitz type protease inhibitor; lipoprotein-associated coagulation inhibitor; OTTHUMP00000163472; OTTHUMP00000205431; unnamed protein product
基因别名: A630013F22Rik; EPI; LACI
UniProt ID: (Mouse) O54819
Entrez Gene ID: (Mouse) 21788
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