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Invitrogen
TGF alpha Polyclonal Antibody
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产品信息
PA1-85931
产品规格
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mature human recombinant TGF-alpha conjugated to KLH
偶联物
形式
Liquid
浓度
3.1 mg/mL
保存条件
4°C or -20°C if preferred
运输条件
Wet ice
RRID
产品详细信息
Sheep anti Human TGF alpha antibody recognizes TGF-alpha (transforming growth factor alpha) from human, rat and bovine tissues and fluids.
靶标信息
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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