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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
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Immunogen sequence: LGKITLVSAA PGKVICEMKV EEEHTNAIGT LHGGLTATLV DNISTMALLC TER
Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 83%.
THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 15kd-p; hotdog-fold thioesterase superfamily member 2; hypothalamus protein HT012; NB4 apoptosis related protein; palmitoyl-CoA hydrolase; thioesterase superfamily member 2; unnamed protein product
基因别名: HT012; PNAS-27; THEM2
UniProt ID: (Human) Q9NPJ3
Entrez Gene ID: (Human) 55856