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Proteintech
THOP1 Monoclonal Antibody (1B11A11)
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THOP1 Antibody (68587-1-IG) in WB
Various lysates were subjected to SDS PAGE followed by western blot with 68587-1-Ig (THOP1 antibody) at dilution of 1:20,000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control.
产品信息
68587-1-IG
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1B11A11
抗原
THOP1 fusion protein Ag2268
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: VEETRYCVDQ NLLKEYFPVQ VVTHGLLGIY QELLGLAFHH EEGASAWHED VRLYTARDAA SGEVVGKFYL DLYPREGKYG HAACFGLQPG CLRQDGSRQI AIAAMVANFT KPTADAPSLL QHDEVETYFH EFGHVMHQLC SQAEFAMFSG THVERDFVEA PSQMLENWVW EQEPLLRMSR HYRTGSAVPR ELLEKLIESR QANTGLFNLR QIVLAKVDQA LHTQTDADPA EEYARLCQEI LGVPATPGTN MPATFGHLAG GYDAQYYGYL WSEVYSMDMF HTRFKQEGVL NSKVGMDYRS CILRPGGSED ASAMLRRFLG RDPKQDAFLL SKGLQVGGCE PEPQVC
靶标信息
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.24; EC 3.4.24.15; Endo-oligopeptidase A; Endopeptidase 24.15; metalloendopeptidase; MP78; PZ-peptidase; Soluble metallo-endopeptidase; Thimet oligopeptidase
基因别名: AI131655; AI327041; EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888, (Mouse) Q8C1A5, (Rat) P24155
Entrez Gene ID: (Human) 7064, (Mouse) 50492, (Rat) 64517
