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PA5-29618 targets Thyroid Hormone Receptor alpha 2 in IF and WB applications and shows reactivity with Human samples.
The PA5-29618 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 251 of Human Thyroid Hormone Receptor alpha 2.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。