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Invitrogen
TIMP1 Monoclonal Antibody (102D1)
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TIMP1 Antibody (MA5-13688) in ICC/IF
Immunofluorescence analysis of TIMP1 was performed using 70% confluent log phase MDA-MB-231 cells treated with Protein Transport Inhibitor (PTI; 1x for 4 hours). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with TIMP1 Monoclonal Antibody (Product # MA5-13688) at 3µg/mL dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly Cross-... View More
产品信息
MA5-13688
应用
建议稀释比
已发表文章
产品规格
已发表种属
C. elegans,
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
102D1
抗原
Recombinant human TIMP-1
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-13688 targets TIMP-1 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-13688 immunogen is recombinant human TIMP-1.
靶标信息
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
