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Invitrogen
TIMP2 Recombinant Rabbit Monoclonal Antibody (PSH11-62)
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TIMP2 Antibody (MA569973) in WB
Western blot analysis of TIMP2 in various lysates. Samples were incubated with TIMP2 monoclonal antibody (Product # MA569973) using a dilution of 1:2,000 in 5% NFDM/TBST at 4°C overnight followed by Goat Anti-Rabbit IgG - HRP Secondary Antibody at a dilution of 1:50,000 for 1 hour at room temperature. Lane 1: SW480 cell lysate; Lane 2: HeLa cell lysate; Lane 3: COS-1 cell lysate. Lysates/proteins at 15 µg/Lane. Predicted band size: 24 kDa; Observed band size: 21 kDa. Exposure time: 1 minute; ECL: K1802; 4-20% SDS-PAGE gel. Proteins were tr... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA569973
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH11-62
抗原
Recombinant protein within human TIMP2 aa 1-220.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: HeLa cell lysate, SW480 cell lysate, COS-1 cell lysate.
Subcellular location: Secreted.
靶标信息
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CSC-21K; Metalloproteinase inhibitor 2; TIMP 2; TIMP-2; Tissue inhibitor of metalloproteinases 2
基因别名: TIMP2
Entrez Gene ID: (Human) 7077
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
