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Invitrogen
TIMP4 Polyclonal Antibody
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产品信息
PA1-25318
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the first loop domain of human TIMP4.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-25318 detects TIMP4 from human samples.
PA1-25318 has been successfully used in Western blot procedures.
The PA1-25318 immunogen is a synthetic peptide corresponding to the first loop domain of human TIMP4.
靶标信息
Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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