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Invitrogen
TIMP4 Polyclonal Antibody
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产品信息
PA1-25320
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminal region of human TIMP4.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-25320 detects TIMP4 from human samples.
PA1-25320 has been successfully used in immunoprecipitation, and Western blot procedures.
The PA1-25320 immunogen is a synthetic peptide corresponding to the C-terminal region of human TIMP4.
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
靶标信息
Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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