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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Based on sequence homology, this antibody may also detect mouse TLR11.
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gm287; MGC129352; MGC129353; toll-like receptor 11; unnamed protein product
基因别名: Gm1365; Tlr11
UniProt ID: (Mouse) Q6QNU9
Entrez Gene ID: (Mouse) 384059