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Abnova
TMED5 Polyclonal Antibody, MaxPab™
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Product Details
H00050999-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMED5 (NP_057124.2, 1 a.a. approximately 229 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGDKIWLPFP VLLLAALPPV LLPGAAGFTP SLDSDFTFTL PAGQKECFYQ PMPLKASLEI EYQVLDGAGL DIDFHLASPE GKTLVFEQRK SDGVHTVETE VGDYMFCFDN TFSTISEKVI FFELILDNMG EQAQEQEDWK KYITGTDILD MKLEDILESI NSIKSRLSKS GHIQILLRAF EARDRNIQES NFDRVNFWSM VNLVVMVVVS AIQVYMLKSL FEDKRKSRT
Target Information
The TMED5 gene encodes the transmembrane emp24 domain-containing protein 5, a member of the TMED family, which is involved in intracellular protein trafficking. This family is essential for the transport of proteins between the endoplasmic reticulum and the Golgi apparatus. TMED5 is a member of the γ subfamily and has been shown to regulate vital cellular processes, including protein secretion and signal transduction. Dysregulation of TMED5 has been implicated in various diseases, including hepatocellular carcinoma (HCC). Increased expression of TMED5 mRNA in HCC tissues is associated with poorer overall survival rates compared to normal tissues, suggesting its role in tumor progression and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p24 family protein gamma-2; p24gamma2; p28; Transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5
Gene Aliases: CGI-100; p24g2; p28; TMED5; UNQ397/PRO733
UniProt ID: (Human) Q9Y3A6
Entrez Gene ID: (Human) 50999
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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