Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
TMEM94 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-52558
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FRMPD4. Recombinant protein control fragment (Product #RP-102448).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PETVLFFSGK VEPPHSSHED LTDGLSTRSF CHPEPHERDA LLAGSLNNTL HLSNEQERGD WPGEAPKPPE PYSHHKAHGR SKHPSGSNTQ PGMESDPYEA EDFVCDYHLE ML
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 79%.
Target Information
TMEM94, also referred to as ERMA, is a multi-pass transmembrane protein located in the endoplasmic reticulum (ER). It plays a crucial role as a P-type ATPase transporter for Mg2+ ions, featuring large cytosolic domains, including actuator, nucleotide, and phosphorylation sections. This gene is vital for embryonic development, particularly for neurological, craniofacial, and cardiac development, as evidenced by studies involving CRISPR-Cas9 deletion in mice, which resulted in impaired neuro and cardiovascular development. Conventional and AlphaFold2 predictions have reinforced the structural complexity of TMEM94, highlighting its significance in cellular magnesium transport and developmental processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Endoplasmic reticulum magnesium ATPase; Transmembrane protein 94
Gene Aliases: ERMA; KIAA0195; TMEM94
UniProt ID: (Human) Q12767
Entrez Gene ID: (Human) 9772
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support