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Invitrogen
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PA1-21148 detects TNF receptor II in human, mouse and rat samples.
PA1-21148 has been successfully used in immunohistochemistry (paraffin), Immunoprecipitation and Western blot procedures.
The PA1-21148 immunogen is a synthetic peptide to the C-terminal region of mouse TNF receptor II protein.
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。