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Abnova
TNXB Monoclonal Antibody (2D3-1B10)
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产品信息
H00007148-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2D3-1B10
抗原
TNXB (AAH33740, 1 a.a. approximately 673 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MRLSWSVAQG PFDSFVVQYE DTNGQPQALL VDGDQSKILI SGLEPSTPYR FLLYGLHEGK RLGPLSAEGT TGLAPAGQTS EESRPRLSQL SVTDVTTSSL RLNWEAPPGA FDSFLLRFGV PSPSTLEPHP RPLLQRELMV PGTRHSAVLR DLRSGTLYSL TLYGLRGPHK ADSIQGTART LSPVLESPRD LQFSEIRETS AKVNWMPPPS RADSFKVSYL LADGGEPQSV QVDGQARTQK LQGLIPGARY EVTVVSVRGF EESEPLTGFL TTVPDGPTQL RALNLTEGFA VLHWKPPQNP VDTYDVQVTA PGAPPLQAET PGSAVDYPLH DLVLHTNYTA TVRGLRGPNL TSPASITFTT GLEAPRDLEA KEVTPRTALL TWTEPPVRPA GYLLSFHTPG GQNQEILLPG GITSHQLLGL FPSTSYNARL QAMWGQSLLP PVSTSFTTGG LRIPFPRDCG EEMQNGAGAS RTSTIFLNGN RERPLNVFCD METDGGGWLV FQRRMDGQTD FWRDWEDYAH GFGNISGEFW LGNEALHSLT QAGDYSMRVD LRAGDEAVFA QYDSFHVDSA AEYYRLHLEG YHGTAGDSMS YHSGSVFSAR DRDPNSLLIS CAVSYRGAWW YRNCHYANLN GLYGSTVDHQ GVSWYHWKGF EFSVPFTEMK LRPRNFRSPA GGG
靶标信息
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: growth-inhibiting protein 45; Hexabrachion-like protein; tenascin XB1; tenascin XB2; Tenascin-X; TN-X; TNXB2tenascin XB1; TNXBSTNXTENX; XB-S; XBTN-X
基因别名: EDS3; HXBL; TENX; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
UniProt ID: (Human) P22105
Entrez Gene ID: (Human) 7148
fatty acid metabolic process
triglyceride metabolic process
cell adhesion
cell-matrix adhesion
single organismal cell-cell adhesion
actin cytoskeleton organization
collagen fibril organization
collagen metabolic process
extracellular fibril organization
regulation of JUN kinase activity
elastic fiber assembly
