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Invitrogen
TOMM20L Polyclonal Antibody
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TOMM20L Antibody (PA5-144064) in WB
Western blot analysis of TOMM20L using TOMM20L antibody (Product # PA5-144064). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human SH-SY5Y whole cell lysates; Lane 2: human A431 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membra... View More
产品信息
PA5-144064
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human TOMM20L (EQPRELLKVFKHTLPPKVFE).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human SH-SY5Y whole cell, human A431 whole cell. Flow: U937 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The TOMM20L gene encodes a protein that is highly related to the translocase of outer mitochondria membrane 20 homolog (TOMM20), which plays a crucial role in the import of mitochondrial preproteins. TOMM20L, likely a paralog or isoform of TOMM20, shares functional similarities and contributes to the complex processes facilitating protein translocation across the outer mitochondrial membrane. This gene's product is integral to the translocase of the outer mitochondrial membrane (TOM) complex, which is essential for maintaining mitochondrial function and biogenesis. TOMM20L assists in the recognition and import of cytosolic precursor proteins into the mitochondria, influencing mitochondrial assembly and function. Although the specific functions of TOMM20L compared to TOMM20 require further elucidation, it is presumed to modulate mitochondrial dynamics and physiology. Alterations in TOMM20L expression could impact mitochondrial efficiency and are relevant in conditions related to energy metabolism and mitochondrial disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog type I
基因别名: TOMM20L; UNQ9438; UNQ9438/PRO34772
UniProt ID: (Human) Q6UXN7
Entrez Gene ID: (Human) 387990
