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Invitrogen
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MA5-12433 targets Topoisomerase II alpha in IHC (P) applications and shows reactivity with Human samples.
The MA5-12433 immunogen is lysate of the human histiocytic leukemia cell line U937.
Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。