Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
TP53INP2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
TP53INP2 Antibody (PA5-75928) in WB
Western blot analysis of TP53INP2 in Lane 1: PC12 whole cell lysate (40 µg), Lane 2: NIH-3T3 whole cell lysate (40 µg), Lane 3: HEK293T whole cell lysate (40 µg), Lane 4: RAW264.7 whole cell lysate (40 µg). Samples were incubated with TP53INP2 polyclonal antibody (Product # PA5-75928) at a dilution of 1:500.
产品信息
PA5-75928
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 148-193 of Human TP53INP2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220 amino acid nuclear protein that is expressed in developing murine brain and spinal cord, as well as in the sensory and motor neuron tracts of the peripheral nervous system. A novel protein involved in the autophagy of mammalian cells, TP53INP2 translocates from the nucleus to the autophagosome structures after activation of autophagy by rapamycin or starvation. Necessary for autophagosome development and considered a scaffold protein, TP53INP2 recruits LC3 and/or LC3-related proteins, such as GABARAP and GABARAP-like2, to the autophagosome membrane by interacting with the transmembrane protein TMEM49. The gene encoding TP53INP2 is located on human chromosome 20, which is comprised of approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: diabetes and obesity regulated; diabetes and obesity-regulated; Diabetes and obesity-regulated gene; Diabetes and obesity-regulated protein; p53-inducible protein U; PIG-U; tumor protein p53 inducible nuclear protein 2; Tumor protein p53-inducible nuclear protein 2
基因别名: 1110029F20Rik; C20orf110; dJ1181N3.1; DOR; PIG-U; PINH; TP53INP2; Trp53inp2
UniProt ID: (Human) Q8IXH6, (Mouse) Q8CFU8
Entrez Gene ID: (Human) 58476, (Rat) 362246, (Mouse) 68728
autophagosome assembly
osteoblast differentiation
tissue homeostasis
transcription, DNA-templated
ubiquitin-dependent protein catabolic process
positive regulation of autophagy
positive regulation of transcription, DNA-templated
negative regulation of cellular protein localization
regulation of transcription, DNA-templated
autophagy
