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Invitrogen
TRHR Polyclonal Antibody
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产品信息
PA5-33088
产品规格
种属反应
Dog,
Horse,
Human,
Sheep,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from C-terminus of human TRH Receptor.
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Sheep, Dog, Elephant, Panda, Horse, Pig (100%); Marmoset, Mouse, Rat, Bovine, Hamster, Opossum, Turkey, Chicken, Lizard, Xenopus (94%); Stickleback (88%); Rabbit, Zebrafish (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC141920; Thyroliberin receptor; Thyrotropin-releasing hormone receptor; TRH receptor; TRH-R; TRH1 Receptor
基因别名: TRH-R; TRH-RECEPTOR; TRHR
UniProt ID: (Human) P34981, (Sheep) Q28596
Entrez Gene ID: (Pig) 100415777, (Dog) 482007, (Human) 7201, (Horse) 100056618, (Sheep) 443425
