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Proteintech

TRIM32 Polyclonal Antibody

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TRIM32 Polyclonal Antibody

产品信息

10326-1-AP

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
查看7篇已发表文章 7篇已发表文章

免疫组化 (IHC)

-
查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200
-

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:20-1:200
-

免疫细胞化学 (ICC/IF)

1:20-1:200
查看3篇已发表文章 3篇已发表文章

免疫沉淀 (IP)

-
查看1篇已发表文章 1篇已发表文章
产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

TRIM32 Fusion Protein Ag0401 (111-430 aa encoded by BC003154)
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.3 mg/mL

规格

45 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: FCRSCGLVL CEPCREADHQ PPGHCTLPVK EAAEERRRDF GEKLTRLREL MGELQRRKAA LEGVSKDLQA RYKAVLQEYG HEERRVQDEL ARSRKFFTGS LAEVEKSNSQ VVEEQSYLLN IAEVQAVSRC DYFLAKIKQA DVALLEETAD EEEPELTASL PRELTLQDVE LLKVGHVGPL QIGQAVKKPR TVNVEDSWAM EATASAASTS VTFREMDMSP EEVVASPRAS PAKQRGPEAA SNIQQCLFLK KMGAKGSTPG MFNLPVSLYV TSQGEVLVAD RGNYRIQVFT RKGFLKEIRR SPSGIDSFVL SFLGADLPNL T (111-430 aa encoded by BC003154)

靶标信息

TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: 72 kDa Tat-interacting protein; bM468K2.2 (tripartite motif protein 32); RING-type E3 ubiquitin transferase TRIM32; RP11-67K19.1; TAT-interactive protein, 72-KD; tripartite motif protein 32; tripartite motif-containing protein 32; unnamed protein product; zinc finger protein 117; zinc-finger protein HT2A

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基因别名: 1810045E12Rik; 3f3; BBS11; HT2A; LGMD2H; LGMDR8; TATIP; Zfp117

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UniProt ID: (Human) Q13049, (Mouse) Q8CH72

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Entrez Gene ID: (Human) 22954, (Rat) 313264, (Mouse) 69807

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功能
transcription coactivator activity RNA binding ubiquitin-protein transferase activity protein binding zinc ion binding myosin binding protein binding, bridging Tat protein binding translation initiation factor binding identical protein binding ubiquitin binding ubiquitin protein ligase activity
参与通路
autophagosome assembly protein polyubiquitination tissue homeostasis ubiquitin-dependent protein catabolic process response to oxidative stress actin ubiquitination biological_process response to UV positive regulation of catabolic process regulation of gene expression positive regulation of autophagy free ubiquitin chain polymerization protein ubiquitination cellular homeostasis positive regulation of cell growth positive regulation of cell migration cellular response to stress negative regulation of toll-like receptor 4 signaling pathway cellular response to amino acid starvation response to tumor necrosis factor response to starvation positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation by host of viral release from host cell innate immune response fat cell differentiation positive regulation of neuron differentiation positive regulation of protein catabolic process positive regulation of cell cycle positive regulation of proteolysis positive regulation of transcription, DNA-templated muscle cell cellular homeostasis negative regulation of fibroblast proliferation positive regulation of neurogenesis positive regulation of striated muscle cell differentiation positive regulation of protein metabolic process axon development protein K63-linked ubiquitination protein K48-linked ubiquitination antiviral innate immune response negative regulation of cilium assembly negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of tumor necrosis factor-mediated signaling pathway positive regulation of interleukin-17-mediated signaling pathway positive regulation of chemokine (C-C motif) ligand 20 production positive regulation of cell motility positive regulation of autophagosome assembly negative regulation of viral transcription toll-like receptor 4 signaling pathway cilium morphogenesis cytosolic ciliogenesis negative regulation of keratinocyte apoptotic process protein localization to phagocytic vesicle
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