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TRIM32 Polyclonal Antibody

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TRIM32 Polyclonal Antibody

产品信息

OST00344W-100UL

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-1:3,000
-

免疫组化（石蜡） (IHC (P))

1:1,000
-

其他PubMed (Misc)

-
查看2篇已发表文章 2篇已发表文章
产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from aa region 160-210 of mouse TRIM32 conjugated to blue carrier protein was used as the antigen
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in rat and shares 95% identity with human sequence.

Specificity of this antibody: TRIM32.

靶标信息

TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: bM468K2.2 (tripartite motif protein 32); RING-type E3 ubiquitin transferase TRIM32; RP11-67K19.1; tripartite motif protein 32; tripartite motif-containing protein 32; unnamed protein product; zinc finger protein 117

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基因别名: 1810045E12Rik; 3f3; BBS11; Zfp117

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UniProt ID: (Mouse) Q8CH72

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Entrez Gene ID: (Rat) 313264, (Mouse) 69807

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功能
transcription coactivator activity RNA binding ubiquitin-protein transferase activity zinc ion binding myosin binding protein binding, bridging translation initiation factor binding identical protein binding ubiquitin binding ubiquitin protein ligase activity protein binding
参与通路
autophagosome assembly protein polyubiquitination tissue homeostasis ubiquitin-dependent protein catabolic process response to oxidative stress actin ubiquitination biological_process response to UV positive regulation of catabolic process regulation of gene expression positive regulation of autophagy free ubiquitin chain polymerization protein ubiquitination cellular homeostasis positive regulation of cell growth positive regulation of cell migration cellular response to stress negative regulation of toll-like receptor 4 signaling pathway cellular response to amino acid starvation response to tumor necrosis factor response to starvation positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation by host of viral release from host cell innate immune response fat cell differentiation positive regulation of neuron differentiation positive regulation of protein catabolic process positive regulation of cell cycle positive regulation of proteolysis positive regulation of transcription, DNA-templated muscle cell cellular homeostasis negative regulation of fibroblast proliferation positive regulation of neurogenesis positive regulation of striated muscle cell differentiation positive regulation of protein metabolic process axon development protein K63-linked ubiquitination protein K48-linked ubiquitination antiviral innate immune response negative regulation of cilium assembly negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of tumor necrosis factor-mediated signaling pathway positive regulation of interleukin-17-mediated signaling pathway positive regulation of chemokine (C-C motif) ligand 20 production positive regulation of cell motility positive regulation of autophagosome assembly negative regulation of viral transcription toll-like receptor 4 signaling pathway cilium morphogenesis cytosolic ciliogenesis negative regulation of keratinocyte apoptotic process protein localization to phagocytic vesicle
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