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Invitrogen
TRPV3 (extracellular) Polyclonal Antibody
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TRPV3 (extracellular) Antibody (PA5-111754) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of TRPV3 in rat DRG primary culture using TRPV3 (extracellular) Antibody (Product # PA5-111754), (1:50-1:100), followed by goat anti-rabbit-AlexaFluor-555 secondary antibody (A). B) Nuclear staining with the cell-permeable dye Hoechst 33342. C) Merged image of panels A and B.
产品信息
PA5-111754
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to aminoa cid residues 464-478 of human TRPV3 (1st extracellular loop)
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)REEEAIP HPLALTHK
Homology: Rat - 13/15 amino acid residues identical; mouse - 12/15 amino acid residues identical.
靶标信息
TRPV3 belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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