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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQSKLDCRS PVGLDCCNCC LDLAHRSGLQ RGSSGENNNP GSPTVSNFRQ LQEKLVFENL NTDKLNSIMR QDSLEPVLRD PCYLINEGIC NRNIDQTMLS ILLFFHSASG ASVVAIDNKI EQAMDLVKNH LMYAVREEVE ILKEQIRELV EKNSQLEREN TLLKTLASPE QLEKFQSCLS PEEPAPESPQ VPEAPGGSAV
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Delta sleep-inducing peptide immunoreactor; DSIP-immunoreactive peptide; GILZ; Glucocorticoid-induced leucine zipper protein; Protein DIP; TSC-22-like protein; TSC-22-related protein; TSC-22R; TSC22 domain family protein 3
基因别名: DSIPI; GILZ; TSC22D3
Entrez Gene ID: (Human) 1831