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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total TTBK1.
TTBK1 is a member of the casein kinase 1 superfamily, and it functions as a neuron-specific serine/threonine and tyrosine kinase. Its primary role is to regulate the phosphorylation of tau, a protein that stabilizes microtubule assemblies. It has been found that genetic variants in this gene are linked to Alzheimer's disease. Additionally, TTBK1 is associated with several other diseases, including Childhood-Onset Schizophrenia and Spinocerebellar Ataxia 11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain-derived tau kinase; RP3-330M21.4; Tau-tubulin kinase 1
基因别名: AU017937; AW048023; BDTK; C330008L01Rik; KIAA1855; TTBK1
UniProt ID: (Mouse) Q6PCN3
Entrez Gene ID: (Mouse) 106763