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Invitrogen
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Immunogen sequence: SLEIGLCVNM RSLPWYVPAN PDSFFPRCYS LCTESEQQEF LEDFRRTMAS SILKWVVSHQ SCSRSSRSKP RDQREEAGSS DLSSRQDAEN AEAKLRGLPG QLVDIACKVC QAYLGQLEHE DIDTSADAVE DLTEAEWEDL TQQYYSLVHG DAFISNSRNY FSQCQALLNR ITSVNPQTDI DGLRNIWII
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 59%.
Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: tubulin tyrosine ligase-like family member 8; tubulin tyrosine ligase-like family, member 8; tubulin--tyrosine ligase-like protein 8
Entrez Gene ID: (Human) 164714