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Proteintech
TUB Polyclonal Antibody
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产品信息
17928-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TUB Fusion Protein Ag12354 (212-561 aa encoded by BC075032)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GQSDHAQDA GETAAGGGER PSGQDLRATM QRKGISSSMS FDEDEEDEEE NSSSSSQLNS NTRPSSATSR KSVREAASAP SPTAPEQPVD VEVQDLEEFA LRPAPQGITI KCRITRDKKG MDRGMYPTYF LHLDREDGKK VFLLAGRKRK KSKTSNYLIS VDPTDLSRGG DSYIGKLRSN LMGTKFTVYD NGVNPQKASS STLESGTLRQ ELAAVCYETN VLGFKGPRKM SVIVPGMNMV HERVSIRPRN EHETLLARWQ NKNTESIIEL QNKTPVWNDD TQSYVLNFHG RVTQASVKNF QIIHGNDPDY IVMQFGRVAE DVFTMDYNYP LCALQAFAIA LSSFDSKLAC E (212-561 aa encoded by BC075032)
靶标信息
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: retinal degeneration 5; tubby homolog; tubby homologue; Tubby protein; Tubby protein homolog
基因别名: Rd5; RDOB; TUB
UniProt ID: (Human) P50607, (Mouse) P50586, (Rat) O88808
Entrez Gene ID: (Human) 7275, (Mouse) 22141, (Rat) 25609
phagocytosis
phagocytosis, recognition
sensory perception of sound
photoreceptor cell maintenance
positive regulation of phagocytosis
response to stimulus
retina development in camera-type eye
receptor localization to nonmotile primary cilium
protein localization to ciliary membrane
protein localization to photoreceptor outer segment
phototransduction
detection of visible light
response to hormone
multicellular organismal macromolecule metabolic process
